I found that, academically, it really didn't matter whether I had received a certain grade in a class; it didn't matter too much what schools I wanted to attend... What matters is one's drive, one's intelligence.
Acting on our interests refines our understanding of what we are good at and what we value. The experiences we have along the way sometimes introduce us to new values that enhance and enlarge our vision. The lessons we learn through habits of action test our understanding and teach us to identify what matters in our life.
What now matters most is how we respond to various risks to the survival of humanity. We are creating some of these risks, and discovering how we could respond to these and other risks. If we reduce these risks, and humanity survives the next few centuries, our descendants or successors could end these risks by spreading through this galaxy.Life can be wonderful as well as terrible, and we shall increasingly have the power to make life good. Since human history may be only just beginning, we can expect that future humans, or supra-humans, may achieve some great goods that we cannot now even imagine. In Nietzsche’s words, there has never been such a new dawn and clear horizon, and such an open sea.If we are the only rational beings in the Universe, as some recent evidence suggests, it matters even more whether we shall have descendants or successors during the billions of years in which that would be possible. Some of our successors might live lives and create worlds that, though failing to justify past suffering, would give us all, including some of those who have suffered, reasons to be glad that the Universe exists.